The new highspeed mixer has broadened the range of choices for customers from a lab specific sm5 to a large sized sm600 and designed to meet various gmp standards in different countries. Impellers and choppers are responsible for uniform mixing and granule. Smgh series mixer and granulator is one of the standard process equipments in the solid dosage production procedure in pharmaceutical industry, and is also widely used in chemical, foodstuff industries, etc. High shear mixer granulator rapid mixing for drywet. Better mixing and closed control of granule size will lead to faster tableting speeds. Rapid mixer granulator is used in the pharmaceutical manufacturing in granulation department for granulation, it is used for making a wet mass and then granulating after which drying, sieving and tablet compression has to be done. Weight l b h in kg taphsmgr2t25 25 20 600 0 7 800 taphsmgr2t75 75 60 2150 2450 2400 1500. When used for tableting or coating, granules allow greater compressibility of a powdered material, and reduce or eliminate the dust that comes from working with powder. The equipment is plc automation controlled and well satisfies the current gmp and. China granulator manufacturers select 2020 high quality granulator products in best price from certified chinese plastic machine manufacturers, plastic machinery suppliers, wholesalers and factory on. Chamunda offers high shear mixer granulators, granulator,wet mixing, rapid mixer granulator machine, granulation machine, rapid mixer granulator manufacturer. Rapid mixer granulator is an ideal mixer for pharmaceutical, chemicals and food products, including aqueous and solvent granulation, wax granulation, dry mixing and wet granulation. Rapid mixer granulator manufacturer in india promas engineers. Mixer granulators use a mechanical impeller to cause powder motion, while the granulator as a whole is usually fixed in space.
Rapid mixer granulator rmg alliance rmg also known as high shear mixer and granulator the application is to effectively produce and uniform, dense granulate operation. Chamunda offers high shear mixer granulators, granulator,wet mixing,rapid mixer granulator machine, granulation machine, rapid mixer granulator manufacturer. Mixing chambers in rapid mixer granulator is of 3 types conical shaped, domed shape, and circular shaped although the basic aim behind all the shapes is to eliminate the dead points and wall adhesion i. The resulting wet mass is dried and sometimes passed through a mill to produce granules of a chosen size. To lay down the procedure for operation of rapid mixer granulator. Rapid mixer granulator is designed to work on two decisive factors essential for the powder mixing.
Wet granulation can be accomplished in a mixer granulator. Rapid mixer granulator is designed to achieve excellent mixing and consistent granules at lower operating cost along with higher productivity. Permix is a chineseisraeli cooperative venture with the famous srugo family in israel. Center impellar and high speed chopper head each indepen. For wet granulation, choppers and impellers are mainly responsible in rapid granulator. Jul 04, 2016 in rapid mixer granulator machine do homogeneous mixing of granulation powder uses for production of tablets. The compact table top design allows installation even if only little space is available.
High shear mixer granulator r2t used in industries. Dust free, high free flowing dosing particles, high uniformity of granule size. Diosna 1used diosna model p 250a stainless steel mixer granulator, sn 255009. China granulator, granulator manufacturers, suppliers, price. The manufacturers operation and maintenance manual and sops that cover the set up. Rapid mixer granulator manufacturer in india promas. The granulation is done in a normal high shear processor. Preparing wet granulations in a planetary mixer planetary mixer granulators. Smgh 501200 high shear mixer granulator application. Vitro pharma machinery offering rapid mixer and wet granulator, tablet making machines in. China granulator, granulator manufacturers, suppliers. This 250 liter unit is designed for mixing and wet granulating of tablet masses. During the addition of binder solutions to the powder impeller and chopper are operated at low speed.
The rapid mixer granulator is mixing unit with a bottom entry agitator ad side mounted chopper for granulation. A mechanical impeller moves the powder while a liquid binder is applied onto a. Rapid mixer granulator rmg machine, high shear mixers. Granulation requires the addition of binding fluidadhesiveto a blend of powders. Investigations at an industrial scale on granule and tablet attributes. Smgh 501200 high shear mixer granulator is designed with high platform and hingemounted cone mill.
Roto mix is a high shear mixer granulator designed for the dry mixing of powders and wet granulation. Being the world leader in high shear mixer granulators, tapasyas quest for continuous improvement of the. You can use rapid mixer granulator to blend both wet and dry powders, which it can perform in a broad range of operating conditions such as function without changing pressure zones. Hlsg series high shear mixer granulator is used in pharmaceutical solid dosage area for mixing and granulation application. Stylish external design fashioned in stainless steel 316l also fully satisfies customers.
Prasad raoquote dear par sad, i think you should check following parameters impeller speed chopper speed granulate placebo a. Rapid mix granulator operation and cleaning guide operating principle a rapid mix granulator is a multipurpose mixerprocessor equally suitable for high speed dispersion of dry powders including effervescent powders and their granulation with aqueous or organic solvents. High shear mixer granulatorhigh speed mixer granulator dja. This is achieved by reducing processing time, more homogenous mixing, uniformity of granule size and above all maintaining improved hygiene compliant to gmp norm. Rapid mixer granulator rmg for mixing and granulating operation. Promas engineers is well known organization for manufacturer, supplier and exporter of rapid mixer granulator according to isi guidelines and users requirements. Our advantages over other competitors are 60 years of designedinisrael knowhow plus competitive madeinchina prices.
The mixer granulator has a vertical shaft, to which four sets of impellers are attached at different elevations. High shear mixer granulator, rapid mixer granulator. In pharmaceutical industry rapid mixer granulator plays vital role to mix the ingredients and make granules before compression. Its the major processing equipment in solid dosage production line. Feb 19, 2016 high speed vertical mixer video mix dry powder materials. The p 16 is a laboratory machine for mixing and granulating of wet granules. Rapid mixer granulator is a multipurpose processer equally suitable for high speed dispersion of dry powders, aqueous or solvent granulation, and effervescent products and melt pelletization. This sop shall be applicable for rapid mixer granulator capacity150 liter in granulation area in the production department. The 360degree rotor movement ensures constant, uniform speed and force effect for gentle sizing of the product. This is a vertical shaft granulator with a 10l bowl. Rapid mixer granulator, rmd, mixer granulator, rapid mixer.
Rapid mixer granulator rmg machine, high shear mixers for. Rmgs are extremely quick and efficient mixers of dry powders. I wanna perform performance qualification of rapid mixer granulator rmg. The speed of the fluidpowder at the outside of the rotor will be higher than the speed of the fluidpowder at the center of the rotor. A threebladed impeller was mounted on the bottom of the bowl. Technical specification rapid mixer granulator gmp model models rdrmg100 rdrmg150 rdrmg250 rdrmg400. The continuous ploughshare mixer operates on principle of the mechanically. Riddhi mixer granulator is designed to meet special needs of tablet manufacturing technology. Dear forum members, i wanna perform performance qualification of rapid mixer granulatorrmg.
We fabricate these machines and the all the parts coming in contact with the material, using high grade stainless steel and then duly polish these to ensure their durability. In short, the design of every component and part of high shear mixer granulator will affect performance, efficiency, safety and reliability of the machine. The operating principle is based on agitation of the contents of the bowl at moderate speed and then running the blade of the chopper at high speeds to achieve granulation. A mixergranulator that dries granules in the same equipment without discharging is commonly called a single pot figure 5. High shear mixer granulator r2t 11 high shear mixer granulator r2t tapasyas hsmg enjoys the trust and confidence of customers, the world over, for its unparalleled quality, unique features and reliable performance. Dry mixing is done by adding all ingredients into the rmg by rotation of impeller and chopper at high speed. The initial range of exchange bowls of 1, 2, 4 and 6 l has meanwhile been completed by a small bowl of 0,25 l. Model gross capacity in liters working capacity in liters overall dimensions in mm motor hp approx. An integral component in understanding the fundamental mechanisms of granulation is the powder flow behaviour within mixer granulators. Industrial mixers and blenders, mixing equipment permix. The equipment will be design for suitable of vacuum transfer system for material loading. High shear mixer granulator series is characterized by the compact construction, modern design and all the user and maintenance friendly attributes which form the ergonomics design aspects are essential for a wide range of application.
High shear granulators glatt integrated process solutions. The equipment is made of high quality austenitic stainless steel and set with operating platform, stepladder and safety guardrail. Rapid mixer granulator is used for making wet mass and after that mass is milled by blades to convert into uniform granules, rapid mixer granulator comes in 4 models rdrmg100, rdrmg150, rdrmg250, rdrmg400, from 100 litres to 600 litres. Our clients can avail from us a wide assortment of rapid mixers and wet granulators. Record the equipment identification number, with equipment manufacturer, purchase order, model number, and equipment number. Liquid binder is sprayed or sometimes poured onto the moving powder bed. It is the only granulator that not only meets all the stringent quality requirements of the fda cgmp, but also meets the specific needs of customers, with its, distinct torquebased granulation endpoint determination. A granulator uses either a wet process or a dry process to bind small particles, such as powders, into larger particles. Sejong pharmatech has launched a new sm series highspeed mixer. It is wide used for pharmaceutical industry, foodstuff industry and chemical industry, etc. High shear mixer granulator has been developed for mixing of ingredients used for wet granulation process. Good documentation practice gdocp pq performance qualification prasadraokilli 201107 14. Standard operating procedure of rapid mixer granulator used in manufacturing of granules for tablets.
Buying and selling unused, used and reconditioned high shear granulators. Rapid mixer granulator is designed to achieve excellent mixing and. The rotating sieve mill guarantees optimum sizing results plus excellent flow rates. Powder flow in vertical high shear mixer granulators uq espace. This rmg machine is also known in industries with various key terms as high shear granulation machine, dry powder granulator, wet. Application rapid mixer granulator is a high efficiency equipment that can mix different powder materials and granulate granule in one procedure. Rapid mixer granulator is a high efficiency equipment that can mix different powder materials and granulate granule in one procedure. Rapid mixer granulators are used in different industries such as food, pharmaceutical as well as dry granulation. It is used for dry blending, wet mixing, preparation of dough and granulation, i. Therefore, it is the first thing you must evaluate. Permix a leading supplier of industrial mixers and blending technology, applied in different industries including food, chemical and pharmaceutical.
Among many granulators, the high shear rapid mixer granulator rmg was a very commonly used wet granulator in pharmaceutical industry. In case the manufacturer cannot explain the reason for opting for a specific design, just avoid that rapid mixer granulator. The process parameters derived in the labpilot scaled up into production machines. High shear mixer granulator r2t tapasyas hsmg enjoys the trust and confidence of customers, the world over, for its unparalleled quality, unique features and reliable performance. Working and principle of rapid mixer granulator rmg. The rapid mixer granulator is a multipurpose processor equally suitable for high speed dispersion of dry powders, aqueous or solvent granulations, and effervescent products and melt pelletization. Would you please suggest me what are the checks to be perform in pq of rmg. Rapid mixer granulator the kalptaru rapid mixer granulator designed very fast to dry mixing and making wet granules in the same bowl in only 6 to 20 min. Scaleup of highshear mixer granulators request pdf. The effect of the chopper on granules from wet highshear. The liquid is added at a predetermined rate to the batch while it is being mixed. In rapid mixer granulator, the formation of granules occurs by rising, whirling and tumbling motion of the material. Nov 26, 2016 mixing chambers in rapid mixer granulator is of 3 types conical shaped, domed shape, and circular shaped although the basic aim behind all the shapes is to eliminate the dead points and wall adhesion i. Phoenix equipment is a global buyer and seller of unused, used and reconditioned high shear granulatorsmixers from well known manufacturers like tk fielder,gea pharma systems, gea aeromaticfielder, geacolette, glatt, fluid air pharmx, powrex, diosna, freundvector, ima pharma, key international, procept, bosch.
Single pot a mixergranulator that dries granules in the same equipment without discharging is commonly called a single pot processor. Oct 18, 2011 all trials were performed using a nirofielder pma1 highshear granulator shown schematically in fig. Wet granulation is a common step in the manufacture of many solid dosage pharmaceuticals. All trials were performed using a nirofielder pma1 highshear granulator shown schematically in fig. The equipment is plc automation controlled and well satisfies the current gmp and pharmacy code regulation. Rapid mixer granulator working principle pharma manual. This equipment has functions of mixing, granulation and mill. Preparing wet granulations in a planetary mixer planetary mixergranulators. Tapasyas high shear mixer granulator is designed to meet the special needs of drying of pharmaceuticals formulations and bulk drugs. High shear mixer granulatorhigh speed mixer granulator. In addition, this type of granulation machine is a perfect option for highly cohesive material. High shear mixer granulators rapid mixer granulator rmg.
High shear mixer granulator, rapid mixer granulator manufacturer. Torque curves allowed us to determine the transition between saturation stages of the wet system applying the method described by leuenberger et al. Spinning close to the bottom of mixing bowl, the impeller sets the entire mixture in a whirling, rising, tumbling motion ensuring a quick an even distribution of all dry components, which leads to an even wetting of every granules. Dry powders are first loaded into the rmg by vacuum or gravity total containment. High shear mixer granulator r2t was introduced with the feature of direct drive technology. A rapid mixer granulator usually comprises mixing bowl with a bottom entry agitator or impeller for mixing the materials and a side mounted chopper for granulating the mixture. Rapid mixer granulator is used for granulation in pharmaceutical manufacturing.